Sincalide is a synthetic C-terminal octapeptide identical to the sequences of the endogenous cholecystokinin hormone. Mimic action of cholecystokinin, sincalide induces gallbladder smooth muscle contraction directly, thereby reducing gallbladder size, inducing bile evacuation, and secretion of pancreatic enzymes. In addition, this agent decreases esophageal sphincter tone and delays gastric emptying via cholinergic signaling.
What are the possible side effects of Sincalide?
Kinevac may cause serious side effects including:
swelling of your face, lips, tongue, or throat,
stomach cramps, and
Get medical help right away, if you have any of the symptoms listed above.
The most common side effects of Kinevac include:
stomach pain, and
Clinically, it is commonly used to cooperate with and strengthen pancreatin for pancreatic exocrine function examination.In cholecystography, CCK instead of fat meal can promote intestinal peristalsis and shorten the time of barium meal examination.Can also be used to treat intestinal paralysis.
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