|Molecular Formula:||C20H27NO3||Molecular Weight:||329.43|
|Melting Point:||264 °C||Storage:||2-8°C|
|Appearance:||Powder||Other Name:||Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4α,5α,17β)-|
Trilostane Raw Steroid Powder,
Raw Steroid Powder CAS 13647-35-3,
Anti Estrogen Apis Raw Steroid Powder Trilostane CAS 13647-35-3 for Breast Cancer
|Appearance||White to tan powder.|
|Boiling point||467.02ºC(rough estimate)|
|Density||1.1213 (rough estimate)|
|Specific rotation||25 +137.4° (c = 1 in pyridine)|
|Refractive index||1.5614 (estimate)|
|Storage condition||-20ºC Freezer|
|Shelf life||2 years|
Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase, which plays a role in adrenal steroid biosynthesis. Investigators believe that Arg195 in 3∫-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of 3β-HSD, but not 3β-HSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular production of dihydrotestosterone in LNCaP-FGC prostate cancer cells and inhibiting cortisol biosynthesis in the human adrenal gland. This product serves as a useful tool in steroid biosynthesis research.
Before taking this medicine
The dose of product will be different for different patients. Follow your doctor's orders.
Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
All products are exported for Lab & Research use in legal and Non-patented area only. Products may not be used in human or animals. Individuals are fully responsible for all consequences arising therefrom.
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