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Product Details:
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| CAS No.: | 13647-35-3 | Name: | Trilostane |
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| Molecular Formula: | C20H27NO3 | Molecular Weight: | 329.43 |
| Melting Point: | 264 °C | Storage: | 2-8°C |
| Appearance: | Powder | Other Name: | Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4α,5α,17β)- |
| High Light: | Trilostane Raw Steroid Powder,Raw Steroid Powder CAS 13647-35-3,Anti Estrogen |
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Anti Estrogen Apis Raw Steroid Powder Trilostane CAS 13647-35-3 for Breast Cancer
Product introduction
| Item | Specifications |
| Appearance | White to tan powder. |
| Purity | 99%min |
| Melting point | 264ºC |
| Boiling point | 467.02ºC(rough estimate) |
| Density | 1.1213 (rough estimate) |
| Specific rotation | 25 +137.4° (c = 1 in pyridine) |
| Refractive index | 1.5614 (estimate) |
| Solubility | DMSO: ≥17mg/mL |
| Storage condition | -20ºC Freezer |
| Shelf life | 2 years |
Trilostane is an inhibitor of isoforms 3β-HSD and 3β-HSD2 of the enzyme 3β-hydroxysteroid dehydrogenase, which plays a role in adrenal steroid biosynthesis. Investigators believe that Arg195 in 3∫-HSD versus Pro195 in 3β-HSD2 attributes to the competitive inhibition of 3β-HSD, but not 3β-HSD2 by Trilostane. Research shows that trilostane is effective in suppressing the intracellular production of dihydrotestosterone in LNCaP-FGC prostate cancer cells and inhibiting cortisol biosynthesis in the human adrenal gland. This product serves as a useful tool in steroid biosynthesis research.
Before taking this medicine
The dose of product will be different for different patients. Follow your doctor's orders.
Side effect:Symptoms of overdose include darkening of skin, drowsiness or tiredness, loss of appetite, mental depression, skin rash, and/or vomiting.
All products are exported for Lab & Research use in legal and Non-patented area only. Products may not be used in human or animals. Individuals are fully responsible for all consequences arising therefrom.
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