|Name:||Benzocaine Powder||CAS:||CAS 94-09-7|
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Benzocaine (Benzocaina) is a white needle crystal (CAS No.: 94-09-7, molecular formula: C9H11NO2, molecular weight: 165), melting point of 90-92 ° C, slightly soluble in water, soluble Organic solvent
The local anesthetic intensity of benzocaine is worse than that of Dimethocain e, tetracaine and lidocaine, and slightly stronger than procain e. Therefore, benzocaine does not cause discomfort due to anesthesia when it acts on the mucosa. Benzociane is a fat-soluble drug, so it is also easy to bind to the mucous membrane of the mucous membrane or skin, but it is not easy to penetrate and enter the body to produce toxicity. At the same time, benzocaine is used as a local anesthetic in medicine. It has analgesic and antipruritic effects. It is mainly used for wounds, ulcers, mucosal surfaces and acne anesthesia, pain relief and itching. The ointment can also be used as a nasopharyngeal catheter. Mirror and other lubrication to relieve pain.
The demand for benzocaine in European countries such as Spain, Italy, the United Kingdom and Brazil in South America is high. Most people use benzocaine for medical purposes, and a small number of people use benzociane for experimental research, or mixing with other chemicals, and unconventional uses.
Benzocaine is indicated to treat a variety of pain-related conditions. It may be used for:
Local anesthesia of oral and pharyngeal mucous membranes (sore throat, cold sores, mouth ulcers, toothache, sore gums, denture irritation)
Otic pain (earache)
Surgical or procedural local anesthesia.
Benzocaine is used as a key ingredient in numerous pharmaceuticals:
Some glycerol-based ear medications for use in removing excess wax as well as relieving ear conditions such as otitis media and swimmers ear.
Some previous diet products such as Ayds.
Some condoms designed to prevent premature ejaculation. Benzocaine largely inhibits sensitivity on the penis, and can allow for an erection to be maintained longer (in a continuous act) by delaying ejaculation. Conversely, an erection will also fade faster if stimulus is interrupted.
Benzocaine mucoadhesive patches have been used in reducing orthodontic pain.
In Poland it is included, together with menthol and zinc oxide, in the liquid powder (not to be confused with the liquid face powder) used mainly after mosquito bites. Today's ready made Pudroderm was once used there as pharmaceutical compound.
Pain is caused by the stimulation of free nerve endings. When the nerve endings are stimulated, sodium enters the neuron, causing depolarization of the nerve and subsequent initiation of an action potential. The action potential is propagated down the nerve toward the central nervous system, which interprets this as pain. Benzocaine acts to inhibit the voltage-dependent sodium channels (VDSCs) on the neuron membrane, stopping the propagation of the action potential.
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