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MSDS Avaliable Setipiprant Hair Growth Peptide Cas 866460-33-5

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China Wuhan Senwayer Century Chemical Co., Ltd. certification
China Wuhan Senwayer Century Chemical Co., Ltd. certification
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MSDS Avaliable Setipiprant Hair Growth Peptide Cas 866460-33-5

MSDS Avaliable Setipiprant Hair Growth Peptide Cas 866460-33-5
MSDS Avaliable Setipiprant Hair Growth Peptide Cas 866460-33-5

Large Image :  MSDS Avaliable Setipiprant Hair Growth Peptide Cas 866460-33-5

Product Details:
Place of Origin: china
Brand Name: senwayer
Certification: GMP&ISO
Model Number: Top quality
Payment & Shipping Terms:
Minimum Order Quantity: 100gram
Packaging Details: foil bag, drum, vials
Delivery Time: 4-5days
Payment Terms: Western union/ money gram/bitcoin/bank transfer/Credit card/paypal
Supply Ability: 5000000 KGS /year
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MSDS Avaliable Setipiprant Hair Growth Peptide Cas 866460-33-5

Description
Product Name: Setipiprant CAS No.: 866460-33-5
Molecular Formula: C24H19FN2O3 Molecular Weight: 402.42
Apperance: Powder Melting Point: /
MSDS: Avaliable
High Light:

Hair Growth Peptide Cas 866460-33-5

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Setipiprant Hair Growth Peptide

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setipiprant Cas 866460-33-5

 

Hair Loss Treatment Setipiprant powder cas 866460-33-5

 

 

- Product Description

 

 

Product name

                                        Setipiprant 
CAS no. 866460-33-5
Molecular formula C24H19FN2O3
Molecular weight 402.42
Purity 99%min
COA Please contact with Senwayer freely

 

 
Setipiprant (INN) (developmental code names ACT-129,968, KYTH-105) is a drug originally developed by Actelion which acts as a selective, orally available antagonist of the prostaglandin D2 receptor 2 (DP2). It was initially researched as a treatment for allergies and inflammatory disorders, particularly asthma, but despite being well tolerated in clinical trials and showing reasonable efficacy against allergen-induced airway responses in asthmatic patients, it failed to show sufficient advantages over existing drugs and was discontinued from further development in this application.

However, following the discovery in 2012 that the prostaglandin D2 receptor (DP/PGD2) is expressed at high levels in the scalp of men affected by male pattern baldness, the rights to setipiprant were acquired by Kythera with a view to potentially developing this drug as a novel treatment for baldness, with a previously unexploited mechanism of action. While it is too early to tell whether setipiprant will be an effective treatment for this condition, the favorable pharmacokinetics and relative lack of side effects seen in earlier clinical trials mean that fresh clinical trials for this new application can be conducted fairly quickly.

A phase 2A study is underway to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo and the active comparator, finasteride, in 18 to 41 years old males with androgenetic alopecia.
 
 
 

- Application & Function

 

 
1.For maximum effect, the solution should be in contact with the scalp for hours before being washed out. It does not seem capable of reducing DHT or the enzyme responsible for its accumulation around the hair follicle, 5-aliha reductase.

2.Which are the main causes of male pattern baldness in genetically susceptible individuals. Therefore, when treatment is stopped, the DHT already accumlated around the follicle has its expected effect, and the follicle usually shrinks again and eventually dies.


3.Setipiprant powder can promote hair regrowth,slow or stop hair loss and treat high blood pressure.Setipiprant needs to be applied once or twice daily for hair to be maintained

- Applicaiton/Dosage


Scalp hair loss Acting through DP2, PGD2 can inhibit hair growth, suggesting that this receptor is a potential target for bald treatment. A phase 2A study to evaluate the safety, tolerability, and efficacy of oral setipiprant relative to a placebo in 18 to 49 year old males with androgenetic.Setipiprant proved to be well-tolerated and reasonably effective in reducing allergen-induced airway responses in asthmatic patient clinical trials.

 

 

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Tag:

setipiprant Cas 866460-33-5,

Dutasteride powder CAS 164656-23-9,

Dutasteride powder 99% Purity

Contact Details
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Contact Person: Angie Zhang

Tel: +8613627115097

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