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Product Details:
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| Product Name: | J 147 | Other Name: | J-147 |
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| CAS No: | 1146963-51-0 | MF: | C18H17F3N2O2 |
| MW: | 350.33 | Purity: | 99% Min |
| Shelf Life: | 2 Years | Application: | Pharmaceutical API |
| Sample: | Available | Storage: | Cool And Dry Place |
| High Light: | Pharmaceutical Raw Material J147 Nootropics,Nootropics Powder CAS 1146963-51-0,J147 Nootropic CAS 1146963-51-0 |
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99% Purity Raw Material Pharmaceuticals Nootropics Powder CAS 1146963-51-0 J 147
Product Introduction
| Name | J 147 |
| English synonyms | J-147 |
| CAS Number | 1146963-51-0 |
| Molecular formula | C18H17F3N2O2 |
| Molecular weight | 350.33 |
| EINECS number | / |
Product Description
| Melting point | / |
| Specific Rotation | / |
| Optical Activity | / |
| Boiling point | 412.8±55.0 °C(Predicted) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| Refractive Index | / |
| Solubility | / |
| Storage | / |
| Acidity coefficient (pKa) | 0.80±0.50(Predicted) |
| Color | White to off-white |
Product Function
J-147 was discovered based upon efficacy in multiple cell culture models of age-associated pathologies rather than exclusively amyloid metabolism. It is an exceptionally potent, orally active and broadly neuroprotective compound has the ability to enhance memory in normal animals as well as to prevent memory deficits in Alzheimer's disease (AD) transgenic mice. The neurotrophic and memory-enhancing activities of J147 are associated with an increase in brain derived neurotrophic factor (BDNF) levels and the expression of BDNF responsive proteins, the enhancement of LTP, the preservation of synaptic protein, the reduction of amyloid plaques, etc.
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